Brain Injury
A Case Series of 39 United States Veterans with Mild Traumatic Brain Injury Treated with Hyperbaric Oxygen Therapy

A Case Series of 39 United States Veterans with Mild Traumatic Brain Injury Treated with Hyperbaric Oxygen Therapy

Article cited by Dr. Alison Bested, MD, and her team in Florida have published results of a case series that, once again, proves the power of Hyperbaric Oxygenation to stop suicidal ideation by healing brain wounds. 39 participants reported reduced pain,...

Oxygen and pressure to benefit brain health

Oxygen and pressure to benefit brain health

A recent systematic review published in the journal Frontiers in Neurology discovered that hyperbaric oxygen therapy could be a very effective and safe therapy option for mild traumatic brain injuries (mTBI). The review was conducted by Dr. Paul G. Harch, a clinical...

Clinical Trial – Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury

The purpose of this study is to examine whether 40 hyperbaric oxygen sessions has effect on
long-term symptoms after brain injury. This study will enroll 90 individuals with persistent
problems 6 months to 10 years after a brain injury. These individuals will be randomized to
receive either oxygen or air in a pressurized hyperbaric chamber. Participants will receive
40 daily hyperbaric chamber sessions.

Participants will have a series of tests and questionnaires before they begin their chamber
sessions, after they complete 40 sessions, and 6 months after they joined the study. These
tests include computer-based and pencil-and-paper questionnaires and thinking tests, brain
imaging, a neurological examination, and an eye exam. Participants will also be asked to
provide blood for future research.

After the 6-month tests are complete, all participants will receive 40 hyperbaric oxygen
sessions, then undergo the same tests at 9 months and 12 months.

Clinical Trial – Functional and Anatomical Magnetic Resonance Imaging (MRI) of Chronic Brain Injury and Hyperbaric Oxygen (HBO2) Study Subjects

The purpose of this study is to evaluate Brain MRI (Magnetic Resonance Imaging), and Brain CT
(Computed Tomography) Angiogram data in subjects who participate in the "Hyperbaric Oxygen
for Chronic Stable Brain Injury" (HYBOBI) study. Including information from MRI and CT
studies provide information about whether hyperbaric oxygen improves brain function in
subjects who have had a brain injury. Subjects will complete MR and CT scans twice during the
study. The first MR and CT will be performed prior to the first hyperbaric session of the
HYBOBI study, and the second will be performed within two weeks following the last hyperbaric

Clinical Trial – Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury

The purpose of this study is to discover the feasibility of conducting clinical research in
individuals with chronic sequelae following brain injury who are given hyperbaric oxygen.
This study will also look at the outcome of individuals with a chronic stable brain injury
due to trauma, anoxia (lack of oxygen to the brain), or stroke, who are given hyperbaric
oxygen. Outcome measures testing cognitive (memory, etc.) and functional (balance, strength,
etc.) measures will be performed before the hyperbaric sessions, immediately following them,
and 6 months later. The subject will receive 60 hyperbaric sessions, 60 minutes in the
chamber, to a pressure of 1.5 ATA, once daily, Monday through Friday.

Clinical Trial – Treatment of Traumatic Brain Injury With Hyperbaric Oxygen Therapy

The purpose of this study is to determine if hyperbaric oxygen therapy (HBOT) improves the
cognitive function of OIF/OEF individuals who have chronic mild to moderate traumatic brain
injury (TBI). Cognitive function includes such things as thinking, remembering, recognition,
concentration ability and perception. Traumatic brain injury is common with head injuries
caused by blows to the head, nearby explosions, or concussion. Subjects will be assigned to
an intervention or sham arm. Computer based cognitive tests will be used as outcome measures.
Subjects are enrolled by invitation only.