The 2019-20 coronavirus disease, caused by COVID-19, is an ongoing pandemic.So far, no
specific treatment has proven efficacy. Recent case series reported the use of Hyperbaric
Oxygen Therapy (HBOT) on 5 severe COVID-19 patients who developed respiratory insufficiency.
HBOT mechanisms of tissue oxygenation and anti-inflammatory effect may explain these
The purpose of the current study is the evaluate the efficacy of HBOT in moderate-severe
COVID-19 patients in a randomized controlled manner.