The Aviv clinic, with locations in Florida and Dubai continues to lead and advance the Hyperbaric Oxygen Therapy industry with research and technology. In this article, the importance of how HBOT helps with aging and longevity is explained.
Senescence and the dangers of senescent cells is a hot topic, and in the aging science and research community, there has been significant effort put towards figuring out how to eliminate senescent cells. These aging cells accumulate, resulting in mutations and cancer cells, and don’t function properly, causing inflammation and affecting the surrounding tissue.
“Senolytic drugs have been designed to clear senescent cells, but they haven’t been proven to be effective in human clinical studies,” says Efrati. “The only therapy proven to be effective in a clinical setting is the hyperoxic-hypoxic paradox HBOT protocol.
“After the HBOT protocol, we are able to see a significant decline in senescent cells in blood samples, as well as skin biopsies. For the first time in humans, we were able to reduce the number of senescent cells, in both blood and tissue.”
Efrati explains that in addition, the Aviv team has seen that the HBOT protocol can elongate telomeres, a region of repetitive DNA sequences that protects the ends of chromosomes.
Over time, as cells divide, the telomeres become slightly shorter, and these shortening telomeres is one of the reasons cells may become senescent cells.
“We are not just halting the shortening of telomeres; we are empirically measuring an increase in telomere length,” says Efrati. “This intervention is taking biology back in time at the cellular level to reverse biological aging.”
HBOT supports angiogenesis and blood-brain-barrier integrity restoration – two facts that are incredibly important when it comes to stabilizing and reversing neurological decline.
“Angiogenesis is crucial,” Efrati explains. “The bottleneck that prevents tissue from repairing itself is related to the blood vessels. As we age, our blood vessels experience atherosclerosis and begin to narrow. Other conditions and factors like diabetes, smoking, TBI and stroke can cause the blood vessels to narrow more quickly, cause injury to the blood vessels or completely occlude the blood vessels.”
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