Neurology Live sits down for part 2 with Shai Efrati, MD, the director of the Sagol Center for Hyperbaric Medicine and Research at Yitzhak Shamir Medical Center to discuss his research with hyperbaric oxygen therapy and explored the potential it may hold as a regenerative treatment.

After conducting studies in a number of other conditions, including stroke, early-stage work is now being done to explore hyperbaric oxygen therapy as a possible treatment for patients with mild cognitive impairment, and even dementia.

New data have implied that it may hold promise for those with diseases like Alzheimer and dementia, as a randomized comparison with placebo for 3 months suggested that the oxygen therapy induced cognitive enhancements as evaluated by perfusion magnetic resonance imaging (MRI).

The research was led by Shai Efrati, MD, director, Sagol Center for Hyperbaric Medicine and Research, Yitzhak Shamir Medical Center; and associate professor, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University. All told, it found that a significant group-by-time interaction in global cognitive function was observed compared to control (= .0017), with the most impressive improvements in attention (net effect size = 0.745) and information processing speed (net effect size = 0.788).

Read the full interview here: